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Polynucleotides, also known as nucleic acid polymers, are essential molecules found in all living organisms, playing a fundamental role in the storage and transmission of genetic information. These polymers are composed of repeating units called nucleotides, which consist of a sugar molecule (ribose or deoxyribose), a phosphate group, and a nitrogenous base (adenine, guanine, cytosine, or thymine/uracil).

How it works

Polynucleotides, often abbreviated as PDRN (Polydeoxyribonucleotide), are a type of nucleic acid derived from salmon DNA. In skincare, PDRN is used as an active ingredient in various topical products and injectable treatments to promote skin regeneration and rejuvenation. Here’s how polynucleotides work in skincare:

Cellular Repair and Regeneration: Polynucleotides contain fragments of DNA that are structurally similar to the DNA found in human cells. When applied to the skin, PDRN penetrates the epidermis and stimulates cellular repair and regeneration processes..

Collagen and Elastin Synthesis: PDRN has been shown to stimulate the production of collagen and elastin, two essential proteins that contribute to skin elasticity, firmness, and overall youthfulness.

Anti-Inflammatory Properties: Polynucleotides exhibit anti-inflammatory properties, which can help calm and soothe irritated or inflamed skin.

Improved Skin Hydration: PDRN has hygroscopic properties, meaning it attracts and retains moisture in the skin. By enhancing skin hydration levels, polynucleotides help restore the skin’s natural moisture barrier, prevent water loss, and maintain optimal skin health and elasticity.

In summary, polynucleotides work by stimulating cellular repair and regeneration, promoting collagen and elastin synthesis, reducing inflammation, improving skin hydration, and enhancing the delivery of nutrients into the skin. As a result, PDRN-based skincare products and treatments offer a safe, effective, and versatile solution for rejuvenating and revitalizing the skin, restoring its youthful appearance and vitality.

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I aim to provide clear, concise, and accurate information Polynucleotides  products and their mechanisms of action. My responses are tailored to your inquiries, offering detailed explanations of how these products work to reduce sweating effectively. Additionally, I’m available 24/7 to provide reliable information and assistance whenever you need it, helping you make informed decisions about managing excessive sweating.

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At a glance

Bucks Skin & Self Clinic - FAQ


Frequently asked questions

Polynucleotides are molecules composed of repeating units called nucleotides. They are essential for storing and transmitting genetic information in living organisms.

A polynucleotide consists of three main components: a sugar molecule (ribose or deoxyribose), a phosphate group, and a nitrogenous base (adenine, guanine, cytosine, or thymine/uracil).

DNA (deoxyribonucleic acid) is a double-stranded nucleic acid found in the nucleus of cells, responsible for storing genetic information. RNA (ribonucleic acid) is single-stranded and plays various roles in gene expression, protein synthesis, and regulation.

Polynucleotides serve as the blueprint for protein synthesis and are involved in processes such as DNA replication, transcription, and translation. They also play roles in DNA repair, recombination, and gene regulation.

The sequence of nucleotides in a polynucleotide chain encodes genetic information in the form of a genetic code. This information is transcribed into messenger RNA (mRNA) and translated into proteins by the cellular machinery.


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I initially spoke to a member of Blow Media's team at a trade show and was very impressed with what they had to offer and with the websites they had already built which I was able to look at on my phone as I queued up to speak to somebody. The initial meeting was followed up very promptly that following week with an email and a fully detailed proposal of what they could offer which was very easy to follow, explaining fully all their services and a breakdown of their costs. I had already researched web designers thoroughly and soon realised that Blow Media, from my initial meeting and early correspondance, was the company I was going to use. From day one they were very proactive and led the whole process. Scott the MD came to see us and very quickly fully understood and visualised what we wanted to achieve perfectly. He also recommended a content writer, an SEO company, a company to do some filming in the clinic and a photographer. We used all his contacts other than the photographer which we decided to try and do ourselves but have since decided to use the photographer Blow Media initially recommended as my photography was the only thing I could criticise about my website. I would highly recommend Blow Media and their whole team, I have already instructed them to start work on our second website as our first website is already delivering and the clinic has never been busier.
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